Ages-specific beverage consumption and its association with depression and anxiety disorders: A prospective cohort study in 188,355 participants

• Published in: Journal of affective disorders 2025-02, Vol.371, p.224-233
• Main Authors: Xie, Jiali, Huang, Zhixian, Mo, Yinan, Pan, Yixuan, Ruan, Yubin, Cao, Wen, Chen, Yinuo, Li, Yaojia, Li, Kezheng, Yu, Danqing, Deng, Binbin
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Aged; Anxiety disorders; Anxiety Disorders - epidemiology; Beverage; Beverages - statistics & numerical data; Coffee; Depression - epidemiology; Depression disorders; Depressive Disorder - epidemiology; Diet - statistics & numerical data; Female; Fruit and Vegetable Juices - statistics & numerical data; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pure fruit juices; Risk Factors; Sugar-sweetened beverages; Sugar-Sweetened Beverages - statistics & numerical data; United Kingdom - epidemiology
• ISSN: 0165-0327; 1573-2517; 1573-2517
• DOI: 10.1016/j.jad.2024.11.069

Diet habit is associated with mental health which has been suggested to be an independent risk factor. Nevertheless, evidence concerning the association between beverage consumption and age-specific mental health remains limited. Here we estimate the association between six types of beverages and depression and anxiety disorders. We included 188,355 participants who completed at least one dietary questionnaire and were free of depression and anxiety disorders at baseline from the UK-Biobank. Cox proportional hazard models and substituting analyses were used. (i) During an average of 11.15 years of follow-up, 5884(3.12 %) participants with incident depression and 6445(3.42 %) anxiety disorders were documented. (ii)In individuals aged 1 serving/day) was associated with higher hazard of depression disorders (SSBs: HR 1.14, 95 % CI 1.02–1.28; ASBs: HR 1.23, 95 % CI 1.09–1.38); whereas, intakes of pure fruit/vegetable juices (PiSs) and coffee were associated with lower hazard of depression disorders(PiSs: HR 0.81, 95 % CI 0.72–0.92; coffee: HR 0.88, 95 % CI 0.81–0.96). (iii)In individuals aged ≥60 years, higher intakes of PiSs and coffee were related to lower hazard of depression and anxiety disorders. (iv)Replacing PiSs or coffee with SSBs was significantly associated with reduced depression and anxiety disorders in individuals aged 180,000 participants to unravel the association between beverage consumption and mental disorders.•In people aged