Role of CLE peptide signaling in root-knot nematode parasitism of plants

• Published in: Planta 2025-01, Vol.261 (1), p.3, Article 3
• Main Authors: Fatima, Saba, Zeb, Saeeda Zaima, Tariq, Moh, Nishat, Yasar, Mohamed, Heba I., Siddiqui, Mansoor A.
• Format: Article
• Language: English
• Subjects: Agriculture; Amino acids; Animals; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Biomedical and Life Sciences; Cell interactions; Cell surface receptors; Communication; Ecology; Forestry; Genes; Host-Parasite Interactions; Infections; Intracellular signalling; Kinases; Life Sciences; Nematodes; Parasites; Parasitic diseases; Parasitism; Peptides; Peptides - metabolism; Physiology; Plant diseases; Plant Diseases - parasitology; Plant layout; Plant Proteins - genetics; Plant Proteins - metabolism; Plant Roots - metabolism; Plant Roots - parasitology; Plant Sciences; Plant species; Plants - metabolism; Plants - parasitology; Proteins; Review; Signal Transduction; Signalling systems; Stem cells; Tylenchoidea - physiology
• ISSN: 0032-0935; 1432-2048; 1432-2048
• DOI: 10.1007/s00425-024-04576-y

Main conclusion We summarize recent findings that have provided new insights into the mechanisms underlying CLE signaling systems in the regulation of plant development and phytonematode interactions. CLAVATA3/EMBRYO SURROUNDING REGION-RELATED (CLE) peptides are short sequences consisting of 12 or 13 amino acids characterized by hydroxylated proline residues, and their presence has been demonstrated in various plant species and phytonematodes across multiple paralogous genes. Here, we review recently conducted research to understanding the signaling pathway of CLE peptide during plant development and infection caused by phytonematodes. Cell-to-cell communication is important for the coherent functioning of living organisms. CLE peptides combined with their specific transmembrane receptors to induce downstream intracellular signaling pathways shows divergent modes of action in many developmental processes in variable species. Moreover, CLE peptide was also involved in plant disease mechanism caused by various plant parasitic nematodes.