Perinatal outcomes after selective third-trimester ultrasound screening for small-for-gestational age: prospective cohort study nested within DESiGN randomized controlled trial

In screening for small-for-gestational age (SGA) using third-trimester antenatal ultrasound, there are concerns about the low detection rates and potential for harm caused by both false-negative and false-positive screening results. Using a selective third-trimester ultrasound screening program, thi...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2024-11
Main Authors: Winsloe, C, Elhindi, J, Vieira, M C, Relph, S, Arcus, C G, Coxon, K, Briley, A, Johnson, M, Page, L M, Shennan, A, Marlow, N, Lees, C, Lawlor, D A, Khalil, A, Sandall, J, Copas, A, Pasupathy, D
Format: Article
Language:English
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Summary:In screening for small-for-gestational age (SGA) using third-trimester antenatal ultrasound, there are concerns about the low detection rates and potential for harm caused by both false-negative and false-positive screening results. Using a selective third-trimester ultrasound screening program, this study aimed to investigate the incidence of adverse perinatal outcomes among cases with (i) false-negative compared with true-positive SGA diagnosis and (ii) false-positive compared with true-negative SGA diagnosis. This prospective cohort study was nested within the UK-based DESiGN trial, a prospective multicenter cohort study of singleton pregnancies without antenatally detected fetal anomalies, born at > 24 + 0 to
ISSN:0960-7692
1469-0705
1469-0705
DOI:10.1002/uog.29130