Clinical characteristics and nutritional status of children with Crohn's disease and risk factors for malnutrition

• Published in: Zhongguo dang dai er ke za zhi 2024-11, Vol.26 (11), p.1194
• Main Authors: Li, Dong-Dan, Ye, Xiao-Lin, Wang, Mei-Chen, Huang, Hong-Mei, Yan, Jie, Zhang, Tian-Zhuo, Yu, Fei-Hong, Guan, De-Xiu, Yang, Wen-Li, Xia, Lu-Lu, Wu, Jie
• Format: Article
• Language: Chinese
• Subjects: Adolescent; Child; Child, Preschool; Crohn Disease - complications; Female; Humans; Logistic Models; Male; Malnutrition - etiology; Nutritional Status; Retrospective Studies; Risk Factors
• ISSN: 1008-8830
• DOI: 10.7499/j.issn.1008-8830.2407056

To investigate the nutritional status of children with Crohn's Disease (CD) at diagnosis and its association with clinical characteristics. A retrospective analysis was performed for the clinical data and nutritional status of 118 children with CD who were admitted to Beijing Children's Hospital, Capital Medical University, from January 2016 to January 2024. A multivariate logistic regression analysis was used to investigate the risk factors for malnutrition. A total of 118 children with CD were included, among whom there were 68 boys (57.6%) and 50 girls (42.4%), with a mean age of (11±4) years. Clinical symptoms mainly included recurrent abdominal pain (73.7%, 87/118), diarrhea (37.3%, 44/118), and hematochezia (32.2%, 38/118), and 63.6% (75/118) of the children had weight loss at diagnosis. The incidence rate of malnutrition was 63.6% (75/118), and the children with moderate or severe malnutrition accounted for 67% (50/75). There were 50 children (42.4%) with emaciation, 8 (6.8%) with growth retardation, a