Chloroma of the Cerebellopontine Angle: A Rare Presentation

This article presents a case study of a 7-year-old female patient with a history of acute myelogenous leukemia, previously treated with chemotherapy. The patient developed acute right peripheral facial paralysis and right upper limb weakness, leading to the discovery of an extra-axial solid lesion a...

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Bibliographic Details
Published in:World neurosurgery 2025-02, Vol.194, p.123516, Article 123516
Main Authors: Eli, Gabriel S., Taborda, Matheus H., Teixeira, Bernardo CA
Format: Article
Language:English
Subjects:
Acute myelogenous leukemia
Cerebellopontine Angle
Chloroma
MRI imaging
Pediatric oncology
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Summary:This article presents a case study of a 7-year-old female patient with a history of acute myelogenous leukemia, previously treated with chemotherapy. The patient developed acute right peripheral facial paralysis and right upper limb weakness, leading to the discovery of an extra-axial solid lesion at the right cerebellopontine angle. This lesion extended into adjacent structures with notable contrast enhancement and restricted diffusion on magnetic resonance imaging, indicative of chloroma, an extramedullary solid mass composed of myeloid precursor cells. The article discusses the clinical presentation and radiological findings, emphasizing the importance of magnetic resonance imaging in diagnosis. It details typical imaging characteristics of cerebellopontine angle chloromas and differentiates them from other intracranial tumors.
ISSN:1878-8750
1878-8769
1878-8769
DOI:10.1016/j.wneu.2024.11.099