Effect of submucosal dexamethasone on postoperative pain, swelling and trismus after periodontal surgery: a randomized clinical study

Objective The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone (DEX) on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery (PFS). Methods In this randomized controlled split-mouth study, 25 patie...

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Bibliographic Details
Published in:Clinical oral investigations 2024-12, Vol.28 (12), p.681
Main Authors: Altindal, Dicle, Alsafadi, Anas, Alshujaa, Basem, Talmac, Ahmet Cemil, Ege, Bilal, Calisir, Metin, Alpaslan, Nazli Zeynep
Format: Article
Language:English
Subjects:
Adult
Analgesics
Anti-Inflammatory Agents - therapeutic use
Chewing
Clinical outcomes
Dentistry
Dexamethasone
Dexamethasone - administration & dosage
Dexamethasone - therapeutic use
Edema - prevention & control
Efficiency
Female
Humans
Male
Medicine
Middle Aged
Mouth
Pain
Pain Measurement
Pain, Postoperative - drug therapy
Pain, Postoperative - prevention & control
Periodontics
Postoperative period
Surgery
Surgical Flaps
Treatment Outcome
Trismus - etiology
Trismus - prevention & control
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Summary:Objective The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone (DEX) on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery (PFS). Methods In this randomized controlled split-mouth study, 25 patients underwent PFS in the mandible, whereby postoperative, submucosal DEX was injected to the surgical field to the test group and submucosal normal saline was applied to the control group. Pain was evaluated using the Visual Analogue Scale (VAS) and the 101-point numeric rate scale in the first 8 h after PFS and on the 2nd, 3rd, 4th, and 7th days, whereas swelling, chewing efficiency, trismus, healing, discomfort and analgesic consumption were evaluated preoperatively on the 1st, 2nd and 7th days. Results In the intergroup evaluation, the VAS-7th hour value of the test group was lower than the control group( p  
ISSN:1432-6981
1436-3771
1436-3771
DOI:10.1007/s00784-024-06076-5