Application of T1-mapping combined with high-spatial-resolution T2-weighted imaging in discriminating mucinous from nonmucinous adenocarcinoma in rectal cancer

• Published in: Abdominal radiology (New York) 2024-12
• Main Authors: Liu, Yi-Yan, Wen, Zi-Qiang, Ma, Yu-Ru, Yang, Xin-Yue, Lu, Bao-Lan, Liu, Quan-Meng, Fan, Wen-Jie, Wu, Yun-Zhu, Yu, Shen-Ping, Chen, Yan
• Format: Article
• Language: English
• ISSN: 2366-0058; 2366-0058
• DOI: 10.1007/s00261-024-04728-4

The aim of this study was to evaluate the utility of T1-mapping, high-spatial-resolution T2-weighted imaging (HR-T2WI), and their combined model in distinguishing between adenocarcinoma not otherwise specified (AC) and mucinous adenocarcinoma (MC) in rectal cancer. A total of 55 patients with pathologically confirmed AC and 37 patients with MC were included in the study. Two radiologists independently reviewed the HR-T2WI and provided assessments of histopathological type. Additionally, T1 relaxation times were quantified using whole-tumor volume methods both pre-contrast (T1p) and post-contrast administration (T1e). The absolute reduction in T1 value (T1d) and the percentage reduction (T1d%) were calculated. Receiver operating characteristic curve analysis was performed to evaluate diagnostic efficacy. HR-T2WI demonstrated a sensitivity, specificity, and accuracy of 81.08%, 94.55%, and 89.13%, respectively, in distinguishing rectal MC. T1p, T1e, and T1d values were significantly higher in the MC group compared to the AC group (P