Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis

• Published in: Annals of surgical oncology 2024-12
• Main Authors: Verhoeff, Kevin, Parente, Alessandro, Wang, Yanbo, Wang, Nanya, Wang, Zhicheng, Śledziński, Maciej, Hellmann, Andrzej, Raffaelli, Marco, Pennestrì, Francesco, Sywak, Mark, Papachristos, Alexander J, Palazzo, Fausto F, Sung, Tae-Yon, Kim, Byung-Chang, Lee, Yu-Mi, Eatock, Fiona, Anderson, Hannah, Iacobone, Maurizio, Daukša, Albertas, Makay, Ozer, Turk, Yigit, Atalay, Hafize Basut, van Dijkum, Els J M Nieveen, Engelsman, Anton F, Holscher, Isabelle, Materazzi, Gabriele, Rossi, Leonardo, Becucci, Chiara, Shore, Susannah L, Fung, Clare, Waghorn, Alison, Mihai, Radu, Balasubramanian, Sabapathy P, Pannu, Arslan, Tatarano, Shuichi, Velázquez-Fernández, David, Miller, Julie A, Serrao-Brown, Hazel, Chen, Yufei, Demarchi, Marco Stefano, Djafarrian, Reza, Doran, Helen, Wang, Kelvin, Stechman, Michael J, Perry, Helen, Hubbard, Johnathan, Lamas, Cristina, Mercer, Philippa, MacPherson, Janet, Lumbiganon, Supanut, Calatayud, María, Hanzu, Felicia Alexandra, Vidal, Oscar, Araujo-Castro, Marta, Ojeda, Cesar Minguez, Papavramidis, Theodosios, de Vera Gómez, Pablo Rodríguez, Aldrees, Abdulaziz, Altwjry, Tariq, Valdés, Nuria, Álvarez-Escola, Cristina, García Sanz, Iñigo, Blanco Carrera, Concepción, Manjón-Miguélez, Laura, De Miguel Novoa, Paz, Recasens, Mónica, García Centeno, Rogelio, Robles Lázaro, Cristina, Van Den Heede, Klaas, Van Slycke, Sam, Michalopoulou, Theodora, Aspinall, Sebastian, Melvin, Ross, Lau, Joel Wen Liang, Cheah, Wei Keat, Tang, Man Hon, Oh, Han Boon, Ayuk, John, Sutcliffe, Robert P
• Format: Article
• Language: English
• ISSN: 1534-4681; 1534-4681
• DOI: 10.1245/s10434-024-16591-0

The impact of obesity on outcomes after adrenalectomy for pheochromocytoma is unclear. This study aims to evaluate outcomes after minimally invasive and open adrenalectomy for pheochromocytoma in patients with obesity and to determine factors that may affect outcomes. Patients undergoing adrenalectomy for pheochromocytoma in 46 international centers between 2012 and 2022 were reviewed, analyzing baseline information, length of hospital stay (LOS), and postoperative complications. Obese (body mass index (BMI) ≥ 30 kg/m ) and nonobese patients were compared. Multivariable analysis was utilized to evaluate outcomes and risk factors for complications, LOS, and increased comprehensive complication index (CCI). Of the 2016 patients, 639 (31.7%) had obesity. Operative time (110.0 versus 105.0 min; p = 0.467), conversion to open rate (3.1% versus 4.7%; p = 0.079), estimated blood loss (20.0 versus 20.0 ml, p = 0.088), rate of complications (19.3% versus 20.8%; p = 0.425), and CCI were similar. However, patients with obesity required a median of 1 day longer LOS (4.0 days versus 5.0 days; p