Serum Vitamin D Levels in Patients with Vernal Keratoconjunctivitis: A Systematic Review and Meta-Analysis

To conduct a systematic review and meta-analysis to provide an outline of available data on the association between serum vitamin D levels and vernal keratoconjunctivitis (VKC) and to determine the possible relationship in children. Systematic research on all articles published until July 2023 was c...

Full description

Saved in:
Bibliographic Details
Published in:Ocular immunology and inflammation 2024-12, p.1-8
Main Authors: Daneshvar, Kimia, Chaibakhsh, Samira, Iranpour, Shila, Rahmanipour, Elham, Ghorbani, Sara, Pourazizi, Mohsen, Peyman, Alireza
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To conduct a systematic review and meta-analysis to provide an outline of available data on the association between serum vitamin D levels and vernal keratoconjunctivitis (VKC) and to determine the possible relationship in children. Systematic research on all articles published until July 2023 was conducted in PubMed, SCOPUS, Web of Science, and Embase. All observational-analytical studies that measured vitamin D levels in patients with VKC were included. Extracted data were included in two separate meta-analyses: 1) a meta-analysis on the standardized mean difference (SMD) of vitamin D levels between VKC patients and the control group and 2) a meta-analysis on the prevalence of vitamin D deficiency in VKC patients. Seven relevant studies that included 316 patients, with the mean age of 10.8 3 ± 1.14 years, with VKC were included in this meta-analysis. The mean serum vitamin D level was significantly lower in the patients with VKC as compared with the control group (SMD: -0.92; 95% CI -1.15, -0.69,  
ISSN:0927-3948
1744-5078
1744-5078
DOI:10.1080/09273948.2024.2431663