Association Between Melanoma Metastasis and Metabolic Syndrome: A Cross-Sectional Study in a Chinese Population

Metabolic syndrome (MetS) remains a significant global public health concern. However, the relationship between MetS, its individual components and melanoma metastasis remains unexplored. We analysed the clinical data of 258 Chinese melanoma patients who had not undergo systemic therapy. Binary logi...

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Bibliographic Details
Published in:Pigment cell and melanoma research 2024-12
Main Authors: Sha, Shanshan, Sun, Shuomin, Dong, Liyun, Wei, Haoran, Chen, Weiyu, Dong, Enzhu, Li, Lu, Lan, Jiajia, Li, Jun, Yang, Liu, Chen, Yong, Tao, Juan
Format: Article
Language:English
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Summary:Metabolic syndrome (MetS) remains a significant global public health concern. However, the relationship between MetS, its individual components and melanoma metastasis remains unexplored. We analysed the clinical data of 258 Chinese melanoma patients who had not undergo systemic therapy. Binary logistic regression, adjusted for sex and age, was employed to evaluate the connection between MetS and its components and melanoma metastasis. Of the 258 melanoma patients, 92 met the MetS criteria upon diagnosis. No direct association between MetS and melanoma metastasis was identified. However, specific components of MetS, namely low HDL-cholesterol levels (OR = 2.85, 95% CI:1.50-5.41, p 
ISSN:1755-148X
1755-148X
DOI:10.1111/pcmr.13203