A 4-year follow-up of root canal obturation using a calcium silicate-based sealer and a zinc oxide-eugenol sealer: A randomized clinical trial

• Published in: International endodontic journal 2024-12
• Main Authors: Bardini, Giulia, Bellido, Montse Mercade, Rossi-Fedele, Giampiero, Casula, Laura, Dettori, Claudia, Ideo, Francesca, Cotti, Elisabetta
• Format: Article
• Language: English
• ISSN: 1365-2591; 1365-2591
• DOI: 10.1111/iej.14167

This randomized clinical trial assessed the outcomes of nonsurgical root canal treatment (RCT), comparing a calcium silicate-based sealer (CSBS) with the single-cone technique (SC) with a zinc oxide-eugenol (ZOE) sealer and warm vertical compaction (WVC). Ninety-two single- and multi-rooted teeth were divided into two groups and treated using either the SC with BioRoot™ RCS (BIO) or WVC with Pulp Canal Sealer™ EWT (PCS). Teeth with apical periodontitis (AP) in both groups were further divided into BIOAP and PCSAP subgroups. Standardized instrumentation and disinfection protocols were followed. Periapical index (PAI) was recorded, and clinical and radiographic follow-ups were conducted at 1, 3, 6, 12, 24, and 48 months. Outcomes considered included success rate (under strict and loose criteria), extraction, length of filling, voids, and extrusion rate, as well as changes in PAI score from baseline. Outcome variables and prognostic factors were analysed using binary and multiple logistic regression at p  .05). The pattern of PAI reduction was similar in both groups (p = .806). Treatment using the SC-CSBS technique and the ZOE sealer with the WVC technique demonstrated a similar success rate.