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Prevalence of Arrhythmias in Patients With Coronary Microvascular Dysfunction

Coronary microvascular dysfunction (CMD) is an important cause of angina with nonobstructive coronary arteries (ANOCA). It is unclear whether CMD is associated with arrhythmia. This study aimed to evaluate the prevalence of arrhythmias in patients with ANOCA and CMD compared to those in patients wit...

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Published in:Catheterization and cardiovascular interventions 2024-12
Main Authors: Chitturi, Kalyan R, Kumar, Sant, Hill, Andrew P, Lorente-Ros, Marta, Cellamare, Matteo, Merdler, Ilan, Abusnina, Waiel, Haberman, Dan, Lupu, Lior, Chaturvedi, Abhishek, Ozturk, Sevket Tolga, Cermak, Vijoli, Sawant, Vaishnavi, Zhang, Cheng, Ben-Dor, Itsik, Tsimploulis, Apostolos, Waksman, Ron, Hashim, Hayder D, Case, Brian C
Format: Article
Language:English
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Summary:Coronary microvascular dysfunction (CMD) is an important cause of angina with nonobstructive coronary arteries (ANOCA). It is unclear whether CMD is associated with arrhythmia. This study aimed to evaluate the prevalence of arrhythmias in patients with ANOCA and CMD compared to those in patients with ANOCA without CMD. In this observational study of the Coronary Microvascular Disease Registry (NCT05960474), patients with ANOCA who underwent invasive coronary functional assessment for CMD were included. The diagnosis of arrhythmia was based on 12-lead electrocardiography (ECG), or clinical diagnosis accompanied by ECG evidence within 1 year before CMD evaluation. The study included 262 patients; 66 (25.2%) were CMD-positive. Patients with CMD were older, and there was no difference in history of heart failure and baseline left ventricular ejection fraction compared to those without CMD. Premature atrial contractions (PACs) (25.8% vs. 5.6%; p 
ISSN:1522-726X
1522-726X
DOI:10.1002/ccd.31324