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Human Genetic GLUT1 Deficiency Results in Impaired T Cellular IFN-γ Production

GLUT1 deficiency prevents glucose uptake in T cells resulting in lower intracellular ATP generation and IFNy production.

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Bibliographic Details
Published in:European journal of immunology 2024-12, p.e202451066
Main Authors: Jong, Renske de, Rajendiran, Anandhi, Hriczko, Judit Turyne, Subramanyam, Sudheendra Hebbar, Rein, Alina, Häusler, Martin, Orlikowsky, Thorsten, Wagner, Norbert, Erny, Daniel, Ohl, Kim, Tenbrock, Klaus
Format: Article
Language:English
Online Access:Get full text
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Description
Summary:GLUT1 deficiency prevents glucose uptake in T cells resulting in lower intracellular ATP generation and IFNy production.
ISSN:1521-4141
1521-4141
DOI:10.1002/eji.202451066