Clinical observation of 4 cases of cerebral infarction caused by left ventricular noncompaction

• Published in: The American journal of emergency medicine 2025-03, Vol.89, p.1-4
• Main Authors: Shufeng, Yu, Changyang, Zhong, Yi, Jin, Cong, Wu, Peng, Wang
• Format: Article
• Language: English
• Subjects: Cardiomyopathy; Distal medium vessel occlusion; Excessive trabeculation; Intravenous thrombolysis
• ISSN: 0735-6757; 1532-8171; 1532-8171
• DOI: 10.1016/j.ajem.2024.12.002

Cerebral infarction associated with myocardial hypertrabeculation is a rare condition that requires optimal management to reduce the risk of thromboembolism and stroke. As intravenous thrombolysis (IVT) is a standard treatment for acute ischemic stroke, it is important to investigate whether it is safe and effective in patients with this rare condition. Four patients with cerebral infarction associated with myocardial hypertrabeculation were included. The clinical data of these patients were retrospectively analyzed to investigate the efficacy and safety of IVT in their treatment. The results showed that IVT was safe and effective for all the four adult patients. The treatment process and complications were summarized, and the prognosis was evaluated using the modified Rankin Scale (mRS). at 24 h after IVT, there was no evidence of hemorrhagic transformation on CT scan for any of the four patients in this case report.In addition, the results showed that IVT was effective in reducing the severity of the cerebral infarction in all four patients. The prognosis was evaluated using the modified Rankin Scale (mRS). This case report provides evidence that IVT is safe and effective in the treatment of cerebral infarction associated with myocardial hypertrabeculation in adults.