New Arylalkenyl α-Pyrones from Cryptocarya densiflora

Four previously undescribed arylalkenyl α-pyrones, designated as crydensiones A‒D (1‒4), were isolated from the twigs and leaves of Cryptocarya densiflora. Their structures were determined through comprehensive spectroscopic analyses together with quantum chemical calculations of electronic circular...

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Bibliographic Details
Published in:Chemistry & biodiversity 2024-12, p.e202403120
Main Authors: Meng, Jie, Xue, Jun-Juan, Miao, Lei, Zhang, Yu, Rao, Li, Zhang, Chuan-Rui
Format: Article
Language:English
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Summary:Four previously undescribed arylalkenyl α-pyrones, designated as crydensiones A‒D (1‒4), were isolated from the twigs and leaves of Cryptocarya densiflora. Their structures were determined through comprehensive spectroscopic analyses together with quantum chemical calculations of electronic circular dichroism (ECD) and nuclear magnetic resonance (NMR) data. All isolates were assessed for cytotoxicity against HCT-116 (colon), A549 (lung), and MDA-MB-231 (breast) cancer cell lines; however, none demonstrated significant activity.
ISSN:1612-1880
1612-1880
DOI:10.1002/cbdv.202403120