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Evaluating the Adherent Perinephric Fat Risk Score in East Asian Populations and its Correlation with Non-Alcoholic Fatty Liver Disease
This study evaluated the predictive value of the APF risk score in East Asian patients undergoing open nephrectomy and its correlation with hypertension and NAFLD. A retrospective study used the clinical data of 82 patients who underwent ON between January 2010 and December 2022. Per their APF score...
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Published in: | Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2024-11, p.103806, Article 103806 |
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Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | This study evaluated the predictive value of the APF risk score in East Asian patients undergoing open nephrectomy and its correlation with hypertension and NAFLD.
A retrospective study used the clinical data of 82 patients who underwent ON between January 2010 and December 2022. Per their APF score, patients were categorized into groups A (0–2 points) and B (3–4 points). Logistic regression analyses were used to compare the overall clinical data between the two groups and identify potential risk factors. Intraoperative APF prevalence was significantly higher in group B compared to group A (P < 0.001). Group B patients were older (63.06 ± 8.88 vs. 53.69 ± 15.21 years) and had higher incidences of hypertension (P < 0.001), diabetes (P = 0.002), and NAFLD (P < 0.001). Preoperative CT scans showed significant differences in posterior (P = 0.009) and lateral perinephric fat thickness (P < 0.001), and perinephric stranding (P < 0.001). Group B also had a higher proportion of malignant tumors (P = 0.039). Multivariate logistic regression revealed that NAFLD (OR = 9.053, P = 0.010) and hypertension (OR = 5.181, P = 0.025) were highly correlated with APF risk scores.
In this study, we found that the newly developed APF risk score had significant value in predicting APF in East Asian patients undergoing open nephrectomy. Additionally, NAFLD and hypertension were highly correlated with elevated APF risk scores.
•Predictive Value of APF Risk Score: The newly developed adherent perinephric fat (APF) risk score effectively predicted the prevalence of intraoperative APF in East Asian patients undergoing open nephrectomy, with significantly higher scores in group B (3–4 points) compared to group A (0–2 points) (P < 0.001).•Correlation with Age and Comorbidities: Patients in the higher APF risk score group (group B) were notably older, with a mean age of 63.06 ± 8.88 years, compared to 53.69 ± 15.21 years in group A. Moreover, group B had significantly more patients with hypertension (P < 0.001), diabetes (P = 0.002), and non-alcoholic fatty liver disease (NAFLD) (P < 0.001).•CT Scan Indicators: Preoperative CT scans revealed substantial differences between the two groups in posterior perinephric fat thickness (P = 0.009), lateral perinephric fat thickness (P < 0.001), and perinephric stranding (P < 0.001), indicating higher APF risk in group B.•Association with Malignant Tumors: A higher proportion of malignant tumors was observed in patients with higher APF risk scores |
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ISSN: | 0939-4753 1590-3729 1590-3729 |
DOI: | 10.1016/j.numecd.2024.103806 |