Dairy consumption and premature coronary artery disease onset: Iran premature coronary artery disease (IPAD) study insights

Evidence has argued about the association between dairy intake and premature coronary artery disease (PCAD) development aimed to be discussed in this study. This case-control study was conducted on 813 individuals with PCAD and 471 healthy controls. The dairy intake of participants was assessed by a...

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Bibliographic Details
Published in:Scientific reports 2025-01, Vol.15 (1), p.408
Main Authors: Mohammadifard, Noushin, Asadi, Ali, Zarepur, Ehsan, Paknahad, Mohammad Hossein, Khosravi, Alireza, Hassannejad, Razieh, Kermani-Alghoraishi, Mohammad, Sarrafzadegan, Nizal
Format: Article
Language:English
Subjects:
631/45/287
692/4019/592
Adult
Case-Control Studies
Coronary Artery Disease - epidemiology
Coronary Artery Disease - etiology
Dairy Products
Female
Humanities and Social Sciences
Humans
Iran - epidemiology
Male
Middle Aged
multidisciplinary
Risk Factors
Science
Science (multidisciplinary)
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Summary:Evidence has argued about the association between dairy intake and premature coronary artery disease (PCAD) development aimed to be discussed in this study. This case-control study was conducted on 813 individuals with PCAD and 471 healthy controls. The dairy intake of participants was assessed by a validated semi-quantitative food frequency questionnaire. Binary and ordinal logistic regression was applied to determine the association of dairy intake with PCAD and its severity, respectively. Compared to the first quartile, the highest quartile of total dairy consumption was associated with an increased risk of PCAD [Odds ratio (OR):1.56; 95% confidence interval (95%CI): 1.13, 2.14; P  = 0.008] in the crude model. It was strengthened after full adjustment [OR: 2.44, 95% CI; 1.50,3.97; P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-83072-5