A review on immunoglobulin Y (IgY) conjugated with metal nanoparticles and biomedical uses

Today, the use of nanoparticles has attracted considerable attention in biomedical investigations and applications. Antibody-nanoparticle conjugates have proven to be useful tools for raising accuracy and sensitivity in in vitro diagnostics. IgY antibodies have benefits over different antibodies in...

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Bibliographic Details
Published in:Bioprocess and biosystems engineering 2023-11, Vol.46 (11), p.1533-1538
Main Authors: Dousari, Amin Sadeghi, Hosseininasab, Seyed Soheil, Akbarizadeh, Majid Reza, Naderifar, Mahin, Mahdavi, Amin, Satarzadeh, Naghmeh
Format: Article
Language:English
Subjects:
Allergens
Antibodies
Antigens
Bacteria
Bacterial diseases
Bacterial infections
bioprocessing
Biotechnology
birds
Chemistry
Chemistry and Materials Science
Chromatography
cost effectiveness
Critical Review
diagnostic techniques
Eggs
Environmental Engineering/Biotechnology
Food Science
Fourier transforms
Gold
Immunoglobulin Y
Immunoglobulins
Industrial and Production Engineering
Industrial Chemistry/Chemical Engineering
mammals
Medical research
Molecular weight
Nanomaterials
Nanoparticles
Nanotechnology
Pathogens
Pharmacy
Polyethylene glycol
toxicology
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Summary:Today, the use of nanoparticles has attracted considerable attention in biomedical investigations and applications. Antibody-nanoparticle conjugates have proven to be useful tools for raising accuracy and sensitivity in in vitro diagnostics. IgY antibodies have benefits over different antibodies in terms of minimizing animal harm, reducing reactivity with mammalian factors, and cost-effective extraction. Metal nanoparticles are widely used for various medical and biological applications and are potential candidates for identifying pathogens and treating them, which can be mostly related to their special properties, including their shape and size. Avian IgY antibodies conjugated with nanoparticles have been widely used for the detection of parasitic, viral, and bacterial infections as well as allergens and toxicological and pharmaceutical molecules. This review aimed to investigate avian antibodies conjugated with metal nanoparticles and their biological applications.
ISSN:1615-7591
1615-7605
DOI:10.1007/s00449-023-02909-x