Recruitment methods for united states Alzheimer disease prevention trials

There are no substantially effective treatments or preventatives for Alzheimer disease. The few prevention trials that were undertaken did not shown efficacy for the drugs tested; but, nevertheless, advanced prevention trials methods. We review past recruitment methods and discuss areas for improvem...

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Bibliographic Details
Published in:The Journal of nutrition, health & aging health & aging, 2012-04, Vol.16 (4), p.331-335
Main Author: Schneider, L. S
Format: Article
Language:English
Subjects:
Adult and adolescent clinical studies
Aging
Alzheimer disease
Alzheimer Disease - drug therapy
Alzheimer Disease - pathology
Alzheimer Disease - prevention & control
Alzheimer's disease
Biological and medical sciences
Biomarkers - analysis
Clinical trials
Clinical Trials as Topic - methods
Cognitive ability
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Dementia
Design
Diabetes
Disease prevention
drugs
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
Geriatrics/Gerontology
Humans
Illnesses
JNHA: Clinical Trials and Aging
Medical sciences
Medicine
Medicine & Public Health
Neurology
Neurosciences
Nutrition
Organic mental disorders. Neuropsychology
Patient Selection
Prescription drugs
Primary Care Medicine
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Quality of Life Research
Research Design
therapeutics
Treatment Outcome
United States
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:There are no substantially effective treatments or preventatives for Alzheimer disease. The few prevention trials that were undertaken did not shown efficacy for the drugs tested; but, nevertheless, advanced prevention trials methods. We review past recruitment methods and discuss areas for improvement. Improvements in recruitment methods can enhance the likelihood for accurately demonstrating the efficacy of an effective drug. Effective therapeutics to prevent AD await discovery and proof.
ISSN:1279-7707
1760-4788
DOI:10.1007/s12603-012-0011-6