In Vivo Toxicity of Industrial Biocide Containing 2,2-Dibromo-3-nitrilopropionamide in Adult and Zebrafish Larvae

2,2-Dibromo-3-nitrilopropionamide (DBNPA) is a widely used biocide with potential environmental implications due to its toxicity. This study aimed to investigate the in vivo toxicity of DBNPA in zebrafish (Danio rerio), a model organism in environmental toxicology. Both adult and larval zebrafish we...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 2024-01, Vol.112 (1), p.2-2, Article 2
Main Authors: Pourshaban-Shahrestani, Ali, Hassan, Jalal, Koohi, Mohammad Kazem
Format: Article
Language:English
Subjects:
adults
Animals
Aquatic ecosystems
Aquatic Pollution
Biocides
Biocompatibility
bulls
Calibration
Danio rerio
Disinfectants - toxicity
Earth and Environmental Science
Ecosystem
Ecotoxicology
Eggs
Embryo, Nonmammalian
Embryogenesis
Embryonic growth stage
Embryos
Environment
Environmental Chemistry
Environmental Health
Environmental impact
Females
In vivo methods and tests
Larva
Larvae
Low concentrations
Morphology
Mortality
Pollution
Skin
Soil Science & Conservation
Toxicity
Toxicology
Veterinary medicine
Waste Water Technology
Water Management
Water Pollutants, Chemical - toxicity
Water Pollution Control
Zebrafish
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Summary:2,2-Dibromo-3-nitrilopropionamide (DBNPA) is a widely used biocide with potential environmental implications due to its toxicity. This study aimed to investigate the in vivo toxicity of DBNPA in zebrafish (Danio rerio), a model organism in environmental toxicology. Both adult and larval zebrafish were exposed to varying concentrations of DBNPA, and significant morphological changes and mortality rates were observed. The study found that even relatively low concentrations of DBNPA can have detrimental effects on zebrafish embryonic development, and high concentrations resulted in rapid mortality in adult zebrafish and larvae. The LC 50 values calculated from this study were 9.3 ppm for adults and 9.1 ppm for larvae, indicating the high toxicity of DBNPA to these organisms. These findings underscore the potential environmental impact of DBNPA and highlight the need for further research into its effects on aquatic ecosystems. Graphical Abstract
ISSN:0007-4861
1432-0800
DOI:10.1007/s00128-023-03824-3