Canine pulmonary clearance during feto-neonatal transition according to the type of delivery

• Published in: Theriogenology 2024-08, Vol.224, p.156-162
• Main Authors: Abreu, Renata Azevedo de, Almeida, Letícia Lima de, Rosa Filho, Roberto Rodrigues da, Angrimani, Daniel de Souza Ramos, Brito, Maíra Morales, Flores, Renato Bueno, Vannucchi, Camila Infantosi
• Format: Article
• Language: English
• Subjects: absorption; Amniotic fluid; Amniotic Fluid - chemistry; Amniotic Fluid - metabolism; animal reproduction; Animals; Animals, Newborn; blood; body temperature; body weight; cesarean section; Cesarean Section - veterinary; distress; Dog; Dogs - physiology; Electrolytes; Female; gas exchange; glucose; heart; hypoxia; lactic acid; liquids; Lung; lung function; Neonatology; Peripartum; Pregnancy; puppies; radiography; risk; thermoregulation
• ISSN: 0093-691X; 1879-3231
• DOI: 10.1016/j.theriogenology.2024.05.022

The success of immediate adaptation to extrauterine life depends on appropriate lung function, however, elective cesarean section can increase the risk of respiratory distress as a result of reduced pulmonary fluid absorption. This study aimed to evaluate the influence of birth mode on pulmonary clearance and respiratory performance of canine neonates in the transition period. For this purpose, 37 neonates were selected according to the obstetric condition: Vaginal Eutocia (n = 17) and Elective C-section (n = 20). Neonates were evaluated for neonatal vitality score, as well as evaluation of heart and respiratory rates, body temperature and body weight, venous hemogasometric evaluation, blood lactate and glucose, pulse oximetry and radiographic evaluation during the first 24 h of life. Additionally, amniotic fluid electrolyte composition of each puppy was evaluated. There was no influence of the type of delivery on electrolyte composition of canine amniotic fluid and neonatal pulmonary liquid content, analyzed by thoracic X-Rays. On the other hand, elective cesarean section delayed pulmonary adaptation, resulting in hypoxemia and less efficient compensatory response to acid-base imbalance and thermoregulation. In conclusion, elective c-section does not delay pulmonary clearance, whilst alters pulmonary adaptation by less efficient gas exchange and lower oxygenation, hindering the compensatory response to acid-base imbalance during the fetal-neonatal transition in dogs. •Elective c-section does not modify radiographic pulmonary content in puppies.•Elective c-section delays clinical pulmonary stabilization after birth in puppies.•Elective c-section hinders the compensatory response to acid-base imbalance.•Elective c-section delays pulmonary efficient gas exchange in puppies.