The different expression patterns of cytokines in Pacific oyster Crassostrea gigas response against bacterial stimulation

Cytokines can be induced by pathogen stimulation for the information exchange between cells, and their expression patterns indicate the response status of cells. In the present study, the expression patterns of ten cytokines (CgIL17–1, −2, −3, −4, −5, −6, CgTNF-1/2, CgTGF-β and CgIFNLP) in haemocyte...

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Bibliographic Details
Published in:Aquaculture 2023-10, Vol.575, p.739743, Article 739743
Main Authors: Zhang, Ziyang, Gao, Lei, Li, Qingsong, Xing, Zhen, Liu, Ranyang, Zhou, Keli, Wang, Lingling, Song, Linsheng
Format: Article
Language:English
Subjects:
apoptosis
aquaculture
Bacterial stimulation
Crassostrea gigas
Cytokine
cytokines
Evaluation
Haemocyte
hemocytes
information exchange
Pacific oyster Crassostrea gigas
pathogens
Vibrio splendidus
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Summary:Cytokines can be induced by pathogen stimulation for the information exchange between cells, and their expression patterns indicate the response status of cells. In the present study, the expression patterns of ten cytokines (CgIL17–1, −2, −3, −4, −5, −6, CgTNF-1/2, CgTGF-β and CgIFNLP) in haemocytes were analyzed in the Pacific oyster Crassostrea gigas after Vibrio splendidus stimulation in the indoor and outdoor experiments to compare the induction patterns of different cytokines and evaluate the response status of haemocytes. After the indoor V. splendidus immersion stimulation, the mRNA abundances of six cytokines (CgIL17–1, −3, −4, −5, CgTGF-β and CgIFNLP) in haemocytes were significantly downregulated at 48 h compared with that in the control group, among which CgIL17–4 was the most down-regulated with 0.009-fold of that in the control group (p 
ISSN:0044-8486
1873-5622
DOI:10.1016/j.aquaculture.2023.739743