Fungal heat shock proteins: molecular phylogenetic insights into the host takeover

Heat shock proteins are constitutively expressed chaperones induced by cellular stress, such as changes in temperature, pH, and osmolarity. These proteins, present in all organisms, are highly conserved and are recruited for the assembly of protein complexes, transport, and compartmentalization of m...

Full description

Saved in:
Bibliographic Details
Published in:Die Naturwissenschaften 2024-04, Vol.111 (2), p.16-16, Article 16
Main Authors: Sagini, João Pedro Nunes, Ligabue-Braun, Rodrigo
Format: Article
Language:English
Subjects:
Adaptability
Adaptation
Biomedical and Life Sciences
Ecology
endothermy
Environment
Evolution
Fungi
gene expression
Heat shock proteins
heat stress
heat-shock protein 40
Hsp40 protein
Hsp70 protein
Hsp90 protein
Life Sciences
Maximum likelihood method
Microorganisms
Original Article
Osmolarity
Phylogenetics
Phylogeny
Phytopathogenic fungi
Protein transport
Proteins
Resistance factors
statistical analysis
temperature
Virulence
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Heat shock proteins are constitutively expressed chaperones induced by cellular stress, such as changes in temperature, pH, and osmolarity. These proteins, present in all organisms, are highly conserved and are recruited for the assembly of protein complexes, transport, and compartmentalization of molecules. In fungi, these proteins are related to their adaptation to the environment, their evolutionary success in acquiring new hosts, and regulation of virulence and resistance factors. These characteristics are interesting for assessment of the host adaptability and ecological transitions, given the emergence of infections by these microorganisms. Based on phylogenetic inferences, we compared the sequences of HSP9, HSP12, HSP30, HSP40, HSP70, HSP90, and HSP110 to elucidate the evolutionary relationships of different fungal organisms to suggest evolutionary patterns employing the maximum likelihood method. By the different reconstructions, our inference supports the hypothesis that these classes of proteins are associated with pathogenic gains against endothermic hosts, as well as adaptations for phytopathogenic fungi.
ISSN:0028-1042
1432-1904
DOI:10.1007/s00114-024-01903-x