Cholangiocarcinoma with carcinomatosis in a sugar glider

A 7-y-old, castrated male, leucistic sugar glider (Petaurus breviceps) was presented because of a progressive history of lethargy, ataxia, diarrhea, and anorexia. Abdominal ultrasound revealed fluid in the abdomen and an infiltrative mass in the liver. Due to a poor prognosis, euthanasia was perform...

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Bibliographic Details
Published in:Journal of veterinary diagnostic investigation 2024-07, Vol.36 (4), p.543-546
Main Authors: Williams, Alyssa L., Brum Rosa, Fabio
Format: Article
Language:English
Subjects:
abdomen
adhesion
Animals
anorexia
Bile Duct Neoplasms - pathology
Bile Duct Neoplasms - veterinary
carcinoma
Cholangiocarcinoma - pathology
Cholangiocarcinoma - veterinary
diaphragm
diarrhea
epithelium
euthanasia
Fatal Outcome
kidneys
liver
Liver Neoplasms - pathology
Liver Neoplasms - veterinary
Male
males
Marsupialia
mesentery
metastasis
necropsy
omentum
Petaurus breviceps
prognosis
stomach
ultrasonics
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Summary:A 7-y-old, castrated male, leucistic sugar glider (Petaurus breviceps) was presented because of a progressive history of lethargy, ataxia, diarrhea, and anorexia. Abdominal ultrasound revealed fluid in the abdomen and an infiltrative mass in the liver. Due to a poor prognosis, euthanasia was performed. Postmortem examination revealed a focally extensive, infiltrative, off-white, firm mass in the liver with adhesion to the omentum, mesentery, gastric serosa, and diaphragm. The remaining hepatic parenchyma was diffusely yellow. Histologically, the hepatic mass was consistent with metastatic cholangiocarcinoma (cholangiocellular carcinoma) with proliferation of neoplastic epithelial cells surrounded by marked desmoplasia. Neoplastic cells expanded and infiltrated the adjacent omentum, mesentery, and the serosal surfaces of the stomach, kidney, and small and large intestines. To our knowledge, cholangiocarcinoma has not been reported previously in a sugar glider.
ISSN:1040-6387
1943-4936
1943-4936
DOI:10.1177/10406387241252815