Human exposures to Brucella canis from a pregnant dog during an international flight: Public health risks, diagnostic challenges and future considerations

• Published in: Zoonoses and public health 2024-09, Vol.71 (6), p.629-641
• Main Authors: Williams, Cara, Swisher, Samantha, Miller, Nicholas, Pinn‐Woodcock, Toby, Austin, Connie, Hsiao, Shih‐Hsuan, Arenas‐Gamboa, Angela M., Tiller, Rebekah, Thacker, Tyler, Taetzsch, Sara, Franklin‐Guild, Rebecca, Cutter, Laurel, Quance, Christine, Hung, Chien‐Che, Maddox, Carol W., Ernst, Mark, Guarino, Cassandra, Lanka, Saraswathi, Garcia‐Gonzalez, Daniel G., Slager, Staci, Sunavala, Zenia, Brown, Clive, Negron, Maria, Pieracci, Emily G.
• Format: Article
• Language: English
• Subjects: Agricultural aircraft; Aircraft; Aircraft compartments; Airlines; Airports; Animal health; Animals; Breeding; Brucella; Brucella canis; Brucella canis - isolation & purification; Brucella melitensis biovar Canis; Brucellosis; Brucellosis - diagnosis; Brucellosis - epidemiology; Brucellosis - transmission; Brucellosis - veterinary; Commercial aircraft; Crew; Diagnostic systems; Disease control; dog diseases; Dog Diseases - diagnosis; Dog Diseases - epidemiology; Dog Diseases - microbiology; Dog Diseases - transmission; Dogs; Domestic animals; Female; fetus; Fetuses; Flight; Government agencies; Health risk assessment; Health risks; Human exposure; human resources; Humans; Illinois; imported communicable diseases; Medical diagnosis; Passengers; pathogens; Personnel; Pregnancy; Public Health; risk; Risk assessment; Travel; Travellers; veterinary clinics; Veterinary services; Zoonoses
• ISSN: 1863-1959; 1863-2378; 1863-2378
• DOI: 10.1111/zph.13121

Aims This report documents the exposure of passengers and crew of a commercial international flight to the zoonotic pathogen Brucella canis after an infected dog aborted in the passenger cabin of the aircraft. This case demonstrates the challenges associated with brucellosis screening and the risks that airline personnel, airport employees and travellers face when animals with unrecognized zoonotic infections are transported. Methods/Results The public health investigation of this case was conducted by the Centers for Disease Control, the Illinois Department of Health and the Illinois Department of Agriculture, in collaboration with a local veterinary clinic and several academic and federal diagnostic laboratories. It included an extensive diagnostic evaluation of the dam and aborted foetuses to confirm a diagnosis of canine brucellosis. Passengers, airline personnel and staff from the veterinary clinic where the dogs were treated underwent risk assessments, and clinic staff also received detailed guidance regarding infection prevention practices. Conclusions Animal shelters and breeding programs are recommended to screen dogs routinely for brucellosis, but it is not unusual for domestic or imported animals to have unknown health histories, including the dog's brucellosis status, at the time of purchase, adoption, or re‐homing. Testing recommendations and requirements vary by state, making it challenging for state public health and animal health agencies to monitor and respond appropriately. This case highlights the importance of Brucella spp. screening in sexually intact dogs prior to breeding, purchase, or domestic or international transportation of the dogs. The transportation of pregnant dogs may present a previously unrecognized public health threat in addition to contributing to unnecessary stress and health risks for pregnant animals.