Method of Gas Chromatography–Mass Spectrometry for the Determination of Free Bisphenol A in Ethanol Extracts

A rapid method is developed for the determination of bisphenol A ( BPA ) in ethanolic extracts by gas chromatography–mass spectrometry ( GC–MS ). The GC–MS method has acquired reference status in accredited analytical laboratories in identifying contaminant impurities in food and alcohol products. B...

Full description

Saved in:
Bibliographic Details
Published in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2024-09, Vol.79 (9), p.1289-1295
Main Authors: Rudakov, Ya. O., Selemenev, V. F., Shelekhova, N. V., Rudakov, O. B., Khorokhordin, A. M.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Bioaccumulation
Bisphenol A
Chemistry
Chemistry and Materials Science
Chromatography
Contaminants
derivatization
epoxides
Epoxy resins
Ethanol
Food packaging
food safety
forensic sciences
Free form
Gas chromatography
gas chromatography-mass spectrometry
Human performance
humans
Mass spectrometry
Physical examinations
rapid methods
Scientific imaging
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A rapid method is developed for the determination of bisphenol A ( BPA ) in ethanolic extracts by gas chromatography–mass spectrometry ( GC–MS ). The GC–MS method has acquired reference status in accredited analytical laboratories in identifying contaminant impurities in food and alcohol products. Bisphenol A is used as a monomer in the production of a number of plastics and epoxy resins; in its free form, it can be contained in quantities exceeding the permissible level in food containers. Bisphenol A can accumulate in a human body and cause harmful health effects. The studies were performed on an Agilent 8890 gas chromatograph equipped with a mass selective detector model 5977B and a 30 m long Ultra ALLOY ® -5 UA5-30M-0.25F capillary column. Optimal modes for the determination of bisphenol A in ethanolic extracts were selected. The direct determination of BPA in ethyl solutions without derivatization using GC–MS can be recommended for the development of procedures for monitoring the quality and safety of food packaging, monitoring BPA in alcohol-containing liquids, as well as in forensic medical examination as a reference procedure to confirm the reliability of BPA identification.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934824700643