Calcium absorption by Alaska pollock surimi protein hydrolysate promotes osteoblast differentiation

The calcium‐binding capacity and osteoblast proliferation and differentiation were studied in Alaska pollock surimi hydrolysate (APSH) using a system that mimics the gastrointestinal digestive system. Evaluation of the calcium absorption–promoting ability of APSH revealed that the best calcium‐bindi...

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Bibliographic Details
Published in:Journal of food science 2024-04, Vol.89 (4), p.2482-2493
Main Authors: Eom, TaeKil, Nam, Taek‐Jeong
Format: Article
Language:English
Subjects:
Absorption
Alkaline phosphatase
Binding
bone formation
Bone growth
bone health
bone morphogenetic proteins
Calcium
Calcium absorption
Calcium ions
calcium‐binding peptide
Cbfa-1 protein
Chymotrypsin
collagen
Differentiation
Digestive system
electron microscopy
energy-dispersive X-ray analysis
food science
Fractions
Gadus chalcogrammus
gastrointestinal system
Hormones
Hydrolysates
Hydrolysis
Mineralization
Osteoblastogenesis
Osteoblasts
Osteocalcin
Osteogenesis
Osteopontin
Pepsin
protein hydrolysates
Proteinhydrolysate
Proteins
Scanning electron microscopy
Spectroscopy
Surimi
transcription factors
Trypsin
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Summary:The calcium‐binding capacity and osteoblast proliferation and differentiation were studied in Alaska pollock surimi hydrolysate (APSH) using a system that mimics the gastrointestinal digestive system. Evaluation of the calcium absorption–promoting ability of APSH revealed that the best calcium‐binding ability was achieved after hydrolysis with a combination of pepsin, α‐chymotrypsin, and trypsin, and separation into
ISSN:0022-1147
1750-3841
DOI:10.1111/1750-3841.16988