Ameliorative Effects of Ginger on Allergic Diseases: An Updated Review

• Published in: Molecular nutrition & food research 2024-10, Vol.68 (20), p.e2300899-n/a
• Main Authors: Khaki Vaighan, Mohammad, Shams, Mohammad Hossein, Tatari, Fatemeh, Jafari, Reza, Sohrabi, Seyyed Mohsen, Eskandari, Nahid, Mohammadi, Mohsen
• Format: Article
• Language: English
• Subjects: Air pollution; Allergens; Allergic diseases; allergic rhinitis; Allergies; Antibiotics; antioxidants; asthma; atopic dermatitis; Climate change; diet; drug therapy; food allergy; food research; Genetic disorders; Genetic structure; Ginger; Hypersensitivity; Immune system; Immunomodulation; Immunotherapy; Intestinal microflora; intestinal microorganisms; Microbiomes; Pharmacology; Plant diseases; Population genetics; probability; Side effects; Urban areas
• ISSN: 1613-4125; 1613-4133; 1613-4133
• DOI: 10.1002/mnfr.202300899

The hypersensitivity reaction of the immune system to harmless environmental substances causes allergic diseases. Today, about 22%–30% of the world's population suffers from allergic diseases. Since the probability of change in the genetic structure during the past decades of lives is very low, genetic disorders cannot be blamed for causing allergic diseases. Thus, factors such as air pollution, climate change, change in diet, increased antibiotics consumption, change in the gut microbiome, migration toward urban areas, and increase in airborne allergens should be considered as the main causes of the spread and increase in allergic diseases. Methods of preventing contact with allergens, drug treatment, and allergen‐specific immunotherapy are used to treat allergic diseases. In recent years, the therapeutic efficacy of herbal compounds has been significantly investigated by the scientific community, because these compounds have very few side effects. Ginger is one of the plant compounds that have anti‐inflammatory, antioxidant, and immunomodulatory properties. The ameliorative effects of this plant on allergic diseases have been identified. Therefore, the aim of this short review is to summarize the knowledge, which is available about the ameliorative properties of the compounds found in the ginger plant that can reduce the clinical symptoms of allergic diseases. Medicinal plants have been widely prescribed throughout the world in traditional medicine for thousands of years to treat a wide range of illnesses and disorders. Ginger is one of the plant compounds whose effects on allergic diseases have been determined. In the last two decades, this substance has received much attention due to its anti‐oxidant, anti‐cancer, anti‐microbial, and anti‐inflammatory properties.