Retraction notice to “Intensified mitochondrial hydrogen peroxide release occurs in all brain regions, affects male as well as female Rett mice, and constitutes a life-long burden” [Arch. Biochem. Biophys. 696 (15 December 2020) 10866]

• Published in: Archives of biochemistry and biophysics 2022-12, Vol.732, p.109467-109467, Article 109467
• Main Authors: Adebayo, Olusegun L., Dewenter, Ina, Rinne, Lena, Golubiani, Gocha, Solomonia, Revaz, Müller, Michael
• Format: Article
• Language: English
• Subjects: biochemistry; biophysics; brain; females; fluorescence; hydrogen peroxide; issues and policy; males; mitochondria
• ISSN: 0003-9861; 1096-0384
• DOI: 10.1016/j.abb.2022.109467

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief and Authors. Professor Michael Müller approached the journal explaining that he had encountered an issue in the way the spectrofluorometric data analyses was performed. The normalization of the fluorescence curves to their respective starting points (as explained in Figure 1A) overestimated the changes in Mecp2-mutant mice, which usually started at lower levels. This overestimation applies to Figure 3 A-D as well as Table 2 and Table 3 and altered the outcomes of the study. Both the EiC and the authors agreed that a corrigendum would not be appropriate due to the change in conclusion and that the paper should therefore be retracted. The authors apologise for any confusion this paper may have resulted in.