Faecal Metabolome Profiles in Individuals Diagnosed with Hyperplastic Polyps and Conventional Adenomas

Colorectal cancer (CRC) development is a gradual process in which progressive histological alterations of the intestinal mucosa damage occur over years. This process can be influenced by modifiable external factors such as lifestyle and diet. Most CRC cases (>80%) originate from conventional aden...

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Bibliographic Details
Published in:International journal of molecular sciences 2024-12, Vol.25 (24), p.13324
Main Authors: Valdés, Alberto, Ruiz-Saavedra, Sergio, Salazar, Nuria, Cifuentes, Alejandro, Suárez, Adolfo, Díaz, Ylenia, Del Rey, Carmen González, González, Sonia, de Los Reyes-Gavilán, Clara G
Format: Article
Language:English
Subjects:
Adenoma - metabolism
Adenoma - pathology
Aged
Analysis
Bile
Caffeine
Cancer
Chromatography, High Pressure Liquid
Colonic Polyps - diagnosis
Colonic Polyps - metabolism
Colonic Polyps - pathology
Colonoscopy
Colorectal cancer
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - metabolism
Colorectal Neoplasms - pathology
Development and progression
Fatty acids
Feces - chemistry
Female
Flavonoids
Health aspects
High performance liquid chromatography
Humans
Hyperplasia - metabolism
Lactose
Male
Mass spectrometry
Metabolism
Metabolites
Metabolome
Metabolomics - methods
Microbiota
Microbiota (Symbiotic organisms)
Middle Aged
Physiological aspects
Polyphenols
Polyps
Polyps (Pathology)
Pyrimidines
Sugars
Tandem Mass Spectrometry - methods
Tumors
Citations: Items that this one cites
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Description
Summary:Colorectal cancer (CRC) development is a gradual process in which progressive histological alterations of the intestinal mucosa damage occur over years. This process can be influenced by modifiable external factors such as lifestyle and diet. Most CRC cases (>80%) originate from conventional adenomas through the adenomatous pathway and usually harbour dysplastic cells, whereas the serrated pathway is less frequent (
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms252413324