Comparison of Postoperative Antibiotic Protocols for Pediatric Complicated Appendicitis: A Western Pediatric Surgery Research Consortium Study

There is no consensus on the appropriate duration of postoperative antibiotics for complicated appendicitis in children. Commonly used antibiotic endpoints include normalization of white blood cell count (WBC) or completion of a minimum number of prespecified treatment days. We compared clinical out...

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Bibliographic Details
Published in:Journal of pediatric surgery 2025-04, Vol.60 (4), p.162165, Article 162165
Main Authors: Patwardhan, Utsav M., Kahan, Anastasia, Eldredge, R. Scott, Russell, Katie W., Lee, Justin, Short, Scott S., Padilla, Benjamin, Cairo, Sarah B., Acker, Shannon N., Jensen, Aaron R., Kelley-Quon, Lorraine I., Rothstein, David H., Fialkowski, Elizabeth A., Chao, Stephanie D., Gillory, Lauren, Pandya, Samir, Diaz-Miron, Jose, Ignacio, Romeo C.
Format: Article
Language:English
Subjects:
Antibiotics
Complicated appendicitis
NSQIP
Pediatric
Perforation
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Summary:There is no consensus on the appropriate duration of postoperative antibiotics for complicated appendicitis in children. Commonly used antibiotic endpoints include normalization of white blood cell count (WBC) or completion of a minimum number of prespecified treatment days. We compared clinical outcomes resulting from varying postoperative antibiotic protocols for complicated appendicitis in children. National Surgical Quality Improvement Program Pediatric (NSQIP-P) data from nine children's hospitals was used to identify a retrospective cohort of children (
ISSN:0022-3468
1531-5037
1531-5037
DOI:10.1016/j.jpedsurg.2025.162165