Amperometric lactate biosensors and their application in (sports) medicine, for life quality and wellbeing

. The article reviews the use of electrochemical biosensors for detecting lactate, a key metabolite of the anaerobic glycolytic pathway. This compound plays an important role in (sports) medicine, in the nutritional sector, in food quality control and touches environmental concerns. Amperometric bio...

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Bibliographic Details
Published in:Mikrochimica acta (1966) 2008, Vol.160 (1-2), p.15-55
Main Authors: Nikolaus, Nadia, Strehlitz, Beate
Format: Article
Language:English
Subjects:
Analytical Chemistry
Applied sciences
Biological and medical sciences
Biosensors
Biotechnology
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Electrochemical methods
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
General, instrumentation
Global environmental pollution
Methods. Procedures. Technologies
Microengineering
Nanochemistry
Nanotechnology
Pollution
Review
Various methods and equipments
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Summary:. The article reviews the use of electrochemical biosensors for detecting lactate, a key metabolite of the anaerobic glycolytic pathway. This compound plays an important role in (sports) medicine, in the nutritional sector, in food quality control and touches environmental concerns. Amperometric biosensors offer a sensitive and selective means to monitor organic analytes like lactate. A detailed study on different aspects of amperometric lactate biosensor preparation is described: the main configuration aspects are compiled regarding electrode materials, biorecognition elements, immobilization methods, mediators and cofactors as well as fields of application. Comparative studies are conducted correlating different configuration aspects and performance of the resulting biosensors. This review contains 214 references from the years 1974 to 2007.
ISSN:0026-3672
1436-5073
DOI:10.1007/s00604-007-0834-8