Highly Emissive Self-assembled Organic Nanoparticles having Dual Color Capacity for Targeted Immunofluorescence Labeling

A new benzoxazole molecule has been synthesized and self‐assembled with functionalized diacetylene molecules to obtain well‐defined nanoparticles of 80 nm diameter. The nanoparticles show enhanced fluorescence emission of 38% quantum yield compared to 3% in THF solution. Selective targeting and dual...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2008-03, Vol.20 (6), p.1117-1121
Main Authors: Kim, Hyong-Jun, Lee, Jiseok, Kim, Tae-Hoon, Lee, Taek Seung, Kim, Jinsang
Format: Article
Language:English
Subjects:
ESIPT
Immunofluorescence
Organic Nanoparticles
Self-assembly
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Summary:A new benzoxazole molecule has been synthesized and self‐assembled with functionalized diacetylene molecules to obtain well‐defined nanoparticles of 80 nm diameter. The nanoparticles show enhanced fluorescence emission of 38% quantum yield compared to 3% in THF solution. Selective targeting and dual color visualization of patterned avidin arrays were achieved by using these nanoparticles to demonstrate their promising application for immunofluorescence labeling.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200701601