Biodegradable block copolymers

Recently, block copolymers have got tremendous impetus on the ongoing research in the area of drug delivery technology, due to their capability to provide a biomaterial having a broad range of amphiphilic characteristics, as well as targeting the drugs to specific site. This article is an attempt to...

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Bibliographic Details
Published in:Advanced drug delivery reviews 2001-12, Vol.53 (1), p.23-44
Main Authors: Kumar, Neeraj, Ravikumar, Majeti N.V., Domb, A.J.
Format: Article
Language:English
Subjects:
Animals
Biocompatible Materials - chemical synthesis
Biocompatible Materials - pharmacokinetics
Biodegradable
Biodegradation, Environmental
Block copolymer
Drug Delivery Systems - methods
Drug-targeting
Humans
Hydrogels
Lactates - chemical synthesis
Lactates - pharmacokinetics
Micelles
Microparticles
Nanoparticles
Poly(esters)
Poly(ether ester amide)
Poly(ether-b-ester)
Polyethylene Glycols - chemical synthesis
Polyethylene Glycols - pharmacokinetics
Star-block copolymer
Surface modification
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Summary:Recently, block copolymers have got tremendous impetus on the ongoing research in the area of drug delivery technology, due to their capability to provide a biomaterial having a broad range of amphiphilic characteristics, as well as targeting the drugs to specific site. This article is an attempt to review applications of block copolymers in surface modification, drug targeting, nano and microparticles, hydrogels, micelles etc. The physicochemical properties of block copolymers and various synthetic routes for block copolymers are also discussed.
ISSN:0169-409X
1872-8294
DOI:10.1016/S0169-409X(01)00219-8