The Effect of NaF In Vitro on the Mechanical and Material Properties of Trabecular and Cortical Bone

High doses of sodium fluoride in bones lead to severe softening, by weakening interfacial properties between the inorganic minerals and the organic components, while leaving mineralization unchanged. This leads to reduction of microdamage and associated stress‐whitening pointing to a change in failu...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2009-01, Vol.21 (4), p.451-457
Main Authors: Thurner, Philipp J., Erickson, Blake, Turner, Patricia, Jungmann, Ralf, Lelujian, Jason, Proctor, Alexander, Weaver, James C., Schitter, Georg, Morse, Daniel E., Hansma, Paul K.
Format: Article
Language:English
Subjects:
bone
mechanical testing
microdamage
sodium fluoride
stress-whitening
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Summary:High doses of sodium fluoride in bones lead to severe softening, by weakening interfacial properties between the inorganic minerals and the organic components, while leaving mineralization unchanged. This leads to reduction of microdamage and associated stress‐whitening pointing to a change in failure mode. Accordingly, elastic modulus, failure stress, and indentation‐distance increase are decreased, whereas failure strain is increased.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200801204