Electrocatalytic oxidation and sensitive determination of l-cysteine at a poly(aminoquinone)-carbon nanotubes hybrid film modified glassy carbon electrode

• Published in: Mikrochimica acta (1966) 2008-07, Vol.162 (1-2), p.219-225
• Main Authors: Tu, Xinman, Xie, Qingji, Huang, Zhao, Jia, Xue’en, Ye, Min
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Biological and medical sciences; Biosensors; Biotechnology; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Chromatographic methods and physical methods associated with chromatography; Electrochemical methods; Exact sciences and technology; Fundamental and applied biological sciences. Psychology; Gas chromatographic methods; Methods. Procedures. Technologies; Microengineering; Nanochemistry; Nanotechnology; Original Paper; Spectrometric and optical methods; Various methods and equipments
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-008-0940-2

. Poly(aminoquinone) (PAQ) was synthesized through iodate-oxidation/Michael addition reaction of 1,2-dihydroxybenzene with 4,4′-methylenedianiline and characterized with SEM, FT-IR and UV-Vis techniques. The PAQ-multiwalled carbon nanotubes (MWCNTs) hybrid film modified glassy carbon (GC) electrode showed well-defined redox peaks of the quinone groups of the polymer, which effectively mediated the oxidation of l -cysteine (CySH) in a pH 7.0 phosphate buffer, with an overpotential decrease by ca. 0.26 V (versus bare GC). The PAQ-MWCNTs-Nafion/GC electrode was used for sensitive biosensing to CySH, with a limit of detection of 75 nmol L −1 .