In situ fabrication of a poly-acrylamide membrane in a microfluidic channel

We present a novel technological approach for the in situ realization of a micron-thin poly-acrylamide membrane in the center of a microfluidic channel. The membrane is formed by interfacial polymerization of an inner stream of monomer solution in between two streams of initiator/catalyst solution i...

Full description

Saved in:
Bibliographic Details
Published in:Microelectronic engineering 2008-05, Vol.85 (5-6), p.1083-1085
Main Authors: Orhan, J.-B., Knaack, R., Parashar, V.K., Gijs, M.A.M.
Format: Article
Language:English
Subjects:
Applied fluid mechanics
Exact sciences and technology
Fluid dynamics
Fluidics
Fundamental areas of phenomenology (including applications)
Hydrodynamic focusing
Interfacial polymerization
Microfluidics
Physics
Poly-acrylamide membrane
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We present a novel technological approach for the in situ realization of a micron-thin poly-acrylamide membrane in the center of a microfluidic channel. The membrane is formed by interfacial polymerization of an inner stream of monomer solution in between two streams of initiator/catalyst solution in a hydrodynamic focusing chip. 20μm thick SU-8 structures are used to replicate the chip in poly dimethylsiloxane (PDMS). The chip is fitted within an adaptor allowing easy fluidic connections, temperature control and optical monitoring under a microscope. With this system, we can easily tune the internal stream width from 5 to 100μm, by varying the internal/external flow ratio.
ISSN:0167-9317
1873-5568
DOI:10.1016/j.mee.2007.12.050