Organocatalytic and Enantioselective Direct Vinylogous Michael Addition to Maleimides

An organocatalytic enantioselective direct vinylogous Michael addition of α,α‐dicyanoolefins to maleimide has been developed; the products could be obtained in good yields and high enantioselectivities.

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Bibliographic Details
Published in:Advanced synthesis & catalysis 2008-08, Vol.350 (11-12), p.1796-1800
Main Authors: Lu, Jun, Zhou, Wei-Juan, Liu, Feng, Loh, Teck-Peng
Format: Article
Language:English
Subjects:
Cinchona alkaloids
dicyanoolefins
enantioselective Michael addition
maleimides
organocatalysis
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Description
Summary:An organocatalytic enantioselective direct vinylogous Michael addition of α,α‐dicyanoolefins to maleimide has been developed; the products could be obtained in good yields and high enantioselectivities.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.200800259