Cardiovascular Disease Risk among Atomic Bomb Survivors Exposed In Utero, 1978–2003

• Published in: Radiation research 2008-09, Vol.170 (3), p.269-274
• Main Authors: Tatsukawa, Yoshimi, Nakashima, Eiji, Yamada, Michiko, Funamoto, Sachiyo, Hida, Ayumi, Akahoshi, Masazumi, Sakata, Ritsu, Ross, Norman P., Kasagi, Fumiyoshi, Fujiwara, Saeko, Shore, Roy E.
• Format: Article
• Language: English
• Subjects: Atomic bombs; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Childhood; Disease risk; Dosimetry; Epidemiology; Female; Humans; Hypertension; Japan - epidemiology; Male; Middle Aged; Nuclear Warfare - statistics & numerical data; Patient assessment; Pregnancy; Prenatal Exposure Delayed Effects - epidemiology; Prevalence; Radiation dosage; Radiation Injuries - epidemiology; Radiotherapy; Regular s; Risk Assessment - methods; Risk Factors; Survivors - statistics & numerical data
• ISSN: 0033-7587; 1938-5404
• DOI: 10.1667/RR1434.1

Tatsukawa, Y., Nakashima, E., Yamada, M., Funamoto, S., Hida, A., Akahoshi, M., Sakata, R., Ross, N. P., Kasagi, F., Fujiwara, S. and Shore, R. E. Cardiovascular Disease Risk among Atomic Bomb Survivors Exposed In Utero, 1978–2003. Radiat. Res. 170, 269–274 (2008). Given the well-documented association of in utero radiation exposure with childhood cancer and developmental impairments, the possibility of effects on adult onset diseases is an important issue. The objectives of the present study were to examine the effects of atomic bomb radiation dose on the incidence of hypertension, hypercholesterolemia and cardiovascular disease (myocardial infarction and stroke) among survivors exposed in utero and to compare their risk estimates with those of survivors exposed in childhood (