Xeomin is free from complexing proteins

In contrast to the other botulinum toxin products Xeomin only contains the 150 kD neurotoxin without complexing proteins which have no therapeutic function and don't influence the diffusion of the neurotoxin. In large clinical Phase III studies (blepharospasm and cervical dystonia) Xeomin showe...

Full description

Saved in:
Bibliographic Details
Published in:Toxicon (Oxford) 2009-10, Vol.54 (5), p.697-701
Main Author: Frevert, Jürgen
Format: Article
Language:English
Subjects:
Animal poisons toxicology. Antivenoms
Bacteriology
Biological and medical sciences
Botulinum toxin
Botulinum Toxins - chemistry
Botulinum Toxins, Type A - chemistry
Complexing proteins efficacy
Drug Contamination
Fundamental and applied biological sciences. Psychology
Medical sciences
Microbiology
Neuromuscular Agents - chemistry
Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
Toxicology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In contrast to the other botulinum toxin products Xeomin only contains the 150 kD neurotoxin without complexing proteins which have no therapeutic function and don't influence the diffusion of the neurotoxin. In large clinical Phase III studies (blepharospasm and cervical dystonia) Xeomin showed the same efficacy and profile of adverse events as Botox. Whereas competing product must be stored refrigerated, Xeomin is stable for 3 years at room temperature.
ISSN:0041-0101
1879-3150
DOI:10.1016/j.toxicon.2009.03.010