Activation of Muscarinic Potassium Currents by ATPgammaS in Atrial Cells

A study of the intracellular perfusion of atrial myocytes with adenosine 5'-(gamma-thio) triphosphate (ATPgammaS) discovered that cytosolic application of ATPgammaS can also lead to G-protein activation, thus implying that experiments with ATPgammaS must be interpreted with caution. References.

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Published in:Science (American Association for the Advancement of Science) 1988-10, Vol.242 (4877), p.443-443
Main Authors: Otero, Angela S, Breitwieser, Gerda E, Szabo, Gabor
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Language:English
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Biochemistry
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container_title Science (American Association for the Advancement of Science)
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creator Otero, Angela S
Breitwieser, Gerda E
Szabo, Gabor
description A study of the intracellular perfusion of atrial myocytes with adenosine 5'-(gamma-thio) triphosphate (ATPgammaS) discovered that cytosolic application of ATPgammaS can also lead to G-protein activation, thus implying that experiments with ATPgammaS must be interpreted with caution. References.
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subjects Biochemistry
title Activation of Muscarinic Potassium Currents by ATPgammaS in Atrial Cells
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