Kluyveromyces lactis toxin does not inhibit yeast adenylyl cyclase

Research reports that although the toxin Kluyveromyces lactis does induce G1 cell cycle arrest, its effects on Saccharomyces cerevisiae cells cannot be mediated by inhibition of adenylyl cyclase, and that treated cells never recover from its effects.

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Bibliographic Details
Published in:Nature (London) 1989-10, Vol.341 (6243), p.666-668
Main Authors: White, John H, Butler, Andrew R, Stark, Michael J. R
Format: Article
Language:English
Subjects:
Biochemistry
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Growth, nutrition, metabolism, transports, enzymes. Molecular biology
Microbiology
Mycology
Saccharomyces cerevisiae
Toxins
Yeasts
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Description
Summary:Research reports that although the toxin Kluyveromyces lactis does induce G1 cell cycle arrest, its effects on Saccharomyces cerevisiae cells cannot be mediated by inhibition of adenylyl cyclase, and that treated cells never recover from its effects.
ISSN:0028-0836
1476-4687
DOI:10.1038/341666a0