Integrating Biosensors and Drug Delivery: A Step Closer Toward Scalable Responsive Drug-Delivery Systems

A miniature biosensor immobilized on the backside of a gold lid is protected inside a microfabricated vial. To activate the protected biosensor, the conjugated polymer/gold lid is opened by the application of 800 mV. Both independent sensing and drug delivery from the microvalves are demonstrated.

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2009-02, Vol.21 (6), p.656-660
Main Authors: Tsai, Han-Kuan Anthony, Moschou, Elizabeth A., Daunert, Sylvia, Madou, Marc, Kulinsky, Lawrence
Format: Article
Language:English
Subjects:
BioMEMS
Biosensors
conducting polymers
drug delivery
hydrogels
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Description
Summary:A miniature biosensor immobilized on the backside of a gold lid is protected inside a microfabricated vial. To activate the protected biosensor, the conjugated polymer/gold lid is opened by the application of 800 mV. Both independent sensing and drug delivery from the microvalves are demonstrated.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200801770