RNA Complementary to a Herpesvirus (Alpha) Gene mRNA Is Prominent in Latently Infected Neurons

Herpes Simplex Virus (HSV) establishes latent infections in the neurons of sensory ganglia. It is predicted that the replication cycle of the latent virus is restricted or blocked at some early point. In other systems it is thought that at least some viral encoded proteins that are detectable in lat...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1987-02, Vol.235 (4792), p.1056-1056
Main Authors: Stevens, J G, Wagner, E K, Devi-Rao, G B, Cook, M L, Feldman, L T
Format: Article
Language:English
Subjects:
Herpes simplex virus
Herpes viruses
Herpesvirus
Infections
Medical research
Online Access:Get full text
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Summary:Herpes Simplex Virus (HSV) establishes latent infections in the neurons of sensory ganglia. It is predicted that the replication cycle of the latent virus is restricted or blocked at some early point. In other systems it is thought that at least some viral encoded proteins that are detectable in latently infected cells function to maintain the latent state.
ISSN:0036-8075
1095-9203