3D Cell-Migration Studies using Two-Photon Engineered Polymer Scaffolds

We use two‐photon polymerization to fabricate 3D scaffolds with precise control over pore size and shape for studying cell migration in 3D. These scaffolds allow movement of cells in all directions. The fabrication, imaging, and quantitative analysis method developed here can be used to do systemati...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2008-12, Vol.20 (23), p.4494-4498
Main Authors: Tayalia, Prakriti, Mendonca, Cleber R., Baldacchini, Tommaso, Mooney, David J., Mazur, Eric
Format: Article
Language:English
Subjects:
cell migration
polymer scaffolds
three-dimensional tracking
two-photon photopolymerization
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Description
Summary:We use two‐photon polymerization to fabricate 3D scaffolds with precise control over pore size and shape for studying cell migration in 3D. These scaffolds allow movement of cells in all directions. The fabrication, imaging, and quantitative analysis method developed here can be used to do systematic cell studies in 3D.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200801319