Trypansoma Cruzi Infection Inhibited by Peptides Modeled from a Fibronectin Cell Attachment Domain

The mechanism by which Tryptansoma cruzi, the protozoan parasite that causes Chagas' disease, becomes attached to mammalian cells is not well understood. Fibronectin is thought to participate in the attachment, and in this study the region of fibronectin that interacts with the surface receptor...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1986-10, Vol.234 (4776), p.603-603
Main Authors: Ouaissi, M A, Cornette, J, Afchain, D, Capron, D, Gras-Masse, H, Tartar, A
Format: Article
Language:English
Subjects:
Biochemistry
Disease
Medical research
Parasites
Online Access:Get full text
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Summary:The mechanism by which Tryptansoma cruzi, the protozoan parasite that causes Chagas' disease, becomes attached to mammalian cells is not well understood. Fibronectin is thought to participate in the attachment, and in this study the region of fibronectin that interacts with the surface receptors of T. cruzi trypomastigotes was investigated.
ISSN:0036-8075
1095-9203