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Fiberoptic Confocal Microscopy Using a 1.55-[mu]m Fiber Laser for Multimodal Biophotonics Applications
We have experimentally demonstrated a fiberoptic confocal microscope using a 1.55-mum laser source. A compact and efficient Er-doped fiber laser source and conventional single-mode fiber components were used to construct a near-infrared fiberoptic confocal microscope system with 3-D scanning capabil...
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Published in: | IEEE journal of selected topics in quantum electronics 2008-02, Vol.14 (1), p.82-87 |
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container_title | IEEE journal of selected topics in quantum electronics |
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creator | Kim, Do-Hyun Ilev, I.K Kang, J.U |
description | We have experimentally demonstrated a fiberoptic confocal microscope using a 1.55-mum laser source. A compact and efficient Er-doped fiber laser source and conventional single-mode fiber components were used to construct a near-infrared fiberoptic confocal microscope system with 3-D scanning capability. A broadband 1.55-mum light source was used to reduce fringe patterns and interferences that occur when a highly coherent source is used. Our system showed a lateral resolution as high as 1.1 mum with a 60times objective lens, which is close to the theoretical limit. The system can be used in various multimodal biophotonics platforms including precise 3D imaging, biosensing, and laser tissue ablation due to its high water absorption characteristics while maintaining low thermomechanical and self-focusing damage from high-power lasers. |
doi_str_mv | 10.1109/JSTQE.2007.914589 |
format | article |
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A compact and efficient Er-doped fiber laser source and conventional single-mode fiber components were used to construct a near-infrared fiberoptic confocal microscope system with 3-D scanning capability. A broadband 1.55-mum light source was used to reduce fringe patterns and interferences that occur when a highly coherent source is used. Our system showed a lateral resolution as high as 1.1 mum with a 60times objective lens, which is close to the theoretical limit. The system can be used in various multimodal biophotonics platforms including precise 3D imaging, biosensing, and laser tissue ablation due to its high water absorption characteristics while maintaining low thermomechanical and self-focusing damage from high-power lasers.</description><identifier>ISSN: 1077-260X</identifier><identifier>EISSN: 1558-4542</identifier><identifier>DOI: 10.1109/JSTQE.2007.914589</identifier><language>eng</language><publisher>New York: The Institute of Electrical and Electronics Engineers, Inc. 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A compact and efficient Er-doped fiber laser source and conventional single-mode fiber components were used to construct a near-infrared fiberoptic confocal microscope system with 3-D scanning capability. A broadband 1.55-mum light source was used to reduce fringe patterns and interferences that occur when a highly coherent source is used. Our system showed a lateral resolution as high as 1.1 mum with a 60times objective lens, which is close to the theoretical limit. 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(IEEE)</general><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>F28</scope><scope>FR3</scope></search><sort><creationdate>20080201</creationdate><title>Fiberoptic Confocal Microscopy Using a 1.55-[mu]m Fiber Laser for Multimodal Biophotonics Applications</title><author>Kim, Do-Hyun ; Ilev, I.K ; Kang, J.U</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p583-d12a35ed17f383a1d0c69716c8282125cb30b2542498c020597d09a5c2f8f5f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Do-Hyun</creatorcontrib><creatorcontrib>Ilev, I.K</creatorcontrib><creatorcontrib>Kang, J.U</creatorcontrib><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><jtitle>IEEE journal of selected topics in quantum electronics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Do-Hyun</au><au>Ilev, I.K</au><au>Kang, J.U</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fiberoptic Confocal Microscopy Using a 1.55-[mu]m Fiber Laser for Multimodal Biophotonics Applications</atitle><jtitle>IEEE journal of selected topics in quantum electronics</jtitle><date>2008-02-01</date><risdate>2008</risdate><volume>14</volume><issue>1</issue><spage>82</spage><epage>87</epage><pages>82-87</pages><issn>1077-260X</issn><eissn>1558-4542</eissn><abstract>We have experimentally demonstrated a fiberoptic confocal microscope using a 1.55-mum laser source. A compact and efficient Er-doped fiber laser source and conventional single-mode fiber components were used to construct a near-infrared fiberoptic confocal microscope system with 3-D scanning capability. A broadband 1.55-mum light source was used to reduce fringe patterns and interferences that occur when a highly coherent source is used. Our system showed a lateral resolution as high as 1.1 mum with a 60times objective lens, which is close to the theoretical limit. The system can be used in various multimodal biophotonics platforms including precise 3D imaging, biosensing, and laser tissue ablation due to its high water absorption characteristics while maintaining low thermomechanical and self-focusing damage from high-power lasers.</abstract><cop>New York</cop><pub>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</pub><doi>10.1109/JSTQE.2007.914589</doi><tpages>6</tpages></addata></record> |
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source | IEEE Electronic Library (IEL) Journals |
title | Fiberoptic Confocal Microscopy Using a 1.55-[mu]m Fiber Laser for Multimodal Biophotonics Applications |
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