Hydrogen transfer reduction of ketones using formic acid as a hydrogen donor under hydrothermal conditions

The hydrothermal experiments with ketones and formic acid showed that the hydrogen transfer reduction of ketones can be conducted using formic acid as a hydride donor in the presence of NaOH at 300 ℃. The yield of alcohols was considerably higher at a much lower ratio of hydrogen source to ketones t...

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Bibliographic Details
Published in:Journal of Zhejiang University. A. Science 2009-11, Vol.10 (11), p.1631-1635
Main Authors: Shen, Zheng, Jin, Fang-ming, Zhang, Ya-lei, Wu, Bing, Cao, Jiang-lin
Format: Article
Language:English
Subjects:
Civil Engineering
Classical and Continuum Physics
Engineering
Industrial Chemistry/Chemical Engineering
Mechanical Engineering
NaOH
Science Letters
丙酮酸
多用途车
氢转移
水热条件
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Summary:The hydrothermal experiments with ketones and formic acid showed that the hydrogen transfer reduction of ketones can be conducted using formic acid as a hydride donor in the presence of NaOH at 300 ℃. The yield of alcohols was considerably higher at a much lower ratio of hydrogen source to ketones than the traditional Meerwein-Ponndorf-Verley （MPV） reduction, reaching 60% for isopropanol from acetone and 70% for lactic acid from pyruvic acid. Water molecules may act as a catalyst in the hydrogen transfer reduction of ketones under hydrothermal conditions.
ISSN:1673-565X
1862-1775
DOI:10.1631/jzus.A0920097