The Bioaccessibility of Lead (Pb) from Vacuumed House Dust on Carpets in Urban Residences

Risk assessments for toxicants in environmental media via oral exposure often rely on measurements of total concentration in a collected sample. However, the human digestive system cannot dissolute all of a toxicant present in the binding matrix, and cannot absorb it with nearly 100% efficiency. In...

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Bibliographic Details
Published in:Risk analysis 2006-02, Vol.26 (1), p.125-134
Main Authors: Yu, Chang Ho, Yiin, Lih-Ming, Lioy, Paul J.
Format: Article
Language:English
Subjects:
Bioaccessibility
Bioavailability
Biological Availability
Child
Dust
Dust - analysis
Environmental Pollutants - analysis
Environmental Pollutants - pharmacokinetics
Environmental Pollutants - toxicity
Evaluation
Floors and Floorcoverings
Health risk assessment
house dust
Households
Houses
Housing
Human exposure
Humans
In Vitro Techniques
lead
Lead - analysis
Lead - pharmacokinetics
Lead - toxicity
Lead content
Lead poisoning
Metals
Models, Biological
Particle Size
Risk
Risk Assessment
Studies
Toxicity
Urban Health
Vacuum
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Summary:Risk assessments for toxicants in environmental media via oral exposure often rely on measurements of total concentration in a collected sample. However, the human digestive system cannot dissolute all of a toxicant present in the binding matrix, and cannot absorb it with nearly 100% efficiency. In vitro bioaccessibility has been developed as a method to estimate oral bioavailability of a toxicant using a physiologically‐based extraction procedure. Bioaccessibility measurements are more physiologically relevant than strong acid leaching measurements of concentration. A method for measuring bioaccessible lead in house dust was derived from the bioaccessibility method currently used for heavy metals in contaminated soils. House dust was collected from carpets in typical urban residences. Bioaccessible lead was measured in house dust (
ISSN:0272-4332
1539-6924
DOI:10.1111/j.1539-6924.2006.00710.x