Lessons on transplant survival from a successful model system

Studies on the snail Melampus reveal that connectivity is crucial to the survival of transplanted ganglia. Transplanted CNS ganglia can innervate targets or induce supernumerary structures. Neuron survival is optimized by the neural incorporation that occurs when a transplanted ganglion is substitut...

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Bibliographic Details
Published in:The Behavioral and brain sciences 1995-03, Vol.18 (1), p.63-63
Main Author: Moffett, Stacia B.
Format: Article
Language:English
Subjects:
Open Peer Commentary
Surgery
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Summary:Studies on the snail Melampus reveal that connectivity is crucial to the survival of transplanted ganglia. Transplanted CNS ganglia can innervate targets or induce supernumerary structures. Neuron survival is optimized by the neural incorporation that occurs when a transplanted ganglion is substituted for an excised ganglion. Better provision for the trophic requirements of neurons will improve the success of mammalian fetal transplants.
ISSN:0140-525X
1469-1825
DOI:10.1017/S0140525X00037420